European Monitoring Centre for Drugs and Drug Addiction

While women are underrepresented in the reviewed studies as a proportion of the population overall, they may not be underrepresented as a proportion of the population who present for treatment. There are a few pharmacotherapy candidates for the treatment of AMPH/MA dependence/use disorder that demonstrate some weak positive signals. The most consistent positive findings have been demonstrated with stimulant agonist treatment (dexamphetamine and methylphenidate), naltrexone and topiramate. A single study has investigated ondansetron for the treatment of MA dependence [44]. This four-arm trial assessed different doses of ondansetron (0.5 mg, 2 mg, 8 mg po OD) against placebo in measures of abstinence, use, severity of dependence, withdrawal, craving and retention in treatment. There was no observable difference in any outcome measure between doses or against placebo.

Seventy-nine percent of the reviewed studies excluded participants with comorbid mental health diagnoses or concomitant medications prescribed for comorbid mental health diagnoses. Research suggests that transient psychotic symptoms are observed in up to 40% of MA-using populations [79] and possibly more amongst treatment seekers. Forty-two percent of individuals who had used MA in the prior 12 months also reported being diagnosed or treated for a concurrent mental illness—three times as high as the non-illicit drug-using population [80]. Among MA users, the majority report a lifetime prevalence of depression and anxiety [81].

NA and Other Peer Support Groups for Drug Addiction

Volunteer, become active in your church or faith community, or join a local club or neighborhood group. Talk to friends or family members about craving when it occurs. Talking can be very helpful in pinpointing the source of the craving. Also, talking about craving often helps to discharge and relieve the feeling and will help restore honesty in your relationship. You can learn to manage your problems without falling back on your addiction.

What is an amphetamine related disorder?

Amphetamine-related psychiatric disorders can occur with acute or chronic use. Acute amphetamine use with resultant psychosis can present like a sympathomimetic toxidrome. Vital signs and a detailed history are difficult to obtain secondary to agitation, paranoia, and the extent of psychosis.

Family therapy can also help repair relationships that may have suffered terribly because of the addiction. Even after users stop taking amphetamines, they may still have problems such as aggression, anxiety, and strong cravings for the drugs. No matter how a person takes amphetamines, these drugs hit with a fast high, making the user feel powerful, alert, and energized. Amphetamines (am-FET-eh-meenz)  are very addictive stimulants. Prescription diet pills also fall into this category of drugs. Each person responds differently, and reactions are hard to predict.

Adjusting to life after rehab

Several other nondopaminergic targets are under active investigation as potential targets for drug addiction medication development. One such target is the metabotropic glutamate receptor subtype 5 (mGluR5). Subsequently, efforts in several industrial and academic laboratories have focused on discovering novel high-affinity and selective mGluR5 noncompetitive antagonists/allosteric modulators that have improved bioavailability over MPEP. This has been a formidable challenge, since even small changes in the MPEP structure lead to a loss of activity. The endogenous κ-opioid agonist dynorphin has been implicated in modulating stress via the κ-opioid receptor system.

Amphetamine Addiction

Generally, withdrawal symptoms peak within seven days and then begin to subside, lasting about two weeks on average. Whether the individual is dealing with an amphetamine use disorder or a meth addiction, the first step in breaking free involves the detox and withdrawal phase of recovery. Withdrawal management entails medical oversight and psychological support for the individual as they undergo withdrawal. There is no specific medication for stimulant withdrawal, but certain antidepressants, like Paxil, Prozac and Remeron, have been found to be helpful.

Contact Stonewater to Help With Amphetamine Addiction Treatment

It should not be used in place of the advice of your physician or other qualified healthcare providers. Two studies reviewed examined dexamphetamine as stimulant agonist treatment. The first study reviewed 49 participants with MA dependence and prescribed 110 mg daily sustained-release oral dexamphetamine over 16 weeks. It measured MA use by self-report and analysis of hair, severity of dependence over time and treatment retention—finding no statistically significant difference between the study groups on planned analysis. Post-hoc analysis demonstrated a reduction in MA dependence symptoms in the dexamphetamine arm compared with placebo using the Leeds Dependence Questionnaire [50]. Another study examined sustained-release oral dexamphetamine (30 mg po BD) for 60 MA-dependent participants [35].

  • Usually, the problem starts as a way of increasing productivity on a stressful day at work or studying for an important test.
  • You may need to use a similar drug to relieve or avoid amphetamine withdrawal symptoms.
  • The complications of substance use disorder are broad and may depend on the type of substance use.
  • While no medication has been found to be fully effective in treating amphetamine withdrawal, there are a number of medications that may be used to manage individual symptoms.
  • This means utilizing both evidence-based and experiential therapies.
  • You may relapse after treatment and start using amphetamines again.

Know that doctors and other medical professionals will NOT turn you into the police or “tell” on you. They’re only there to help, so do not hesitate to go to the hospital or take a loved one. If your drug use is out of control or causing problems, talk to your doctor. If you grew how long do amphetamines stay in your system up with family troubles and aren’t close to your parents or siblings, it may raise your chances of addiction. As an older adult, the added pressures of work, family, friendships, and bills can become overwhelming. Victory Bay offers an Older Adults Treatment System (O.A.T.S).


Your email address will not be published. Required fields are marked *